Study of 25,000 psychedelic support hotline calls finds cannabis linked to highest distress rate

A study in Science Advances analysed 25,419 anonymised interactions with volunteers on the Fireside Project's Psychedelic Support Line between April 2021 and February 2026. Callers who had used cannabis reported the highest distress rate (47.2 percent), and 43 calls described 'facilitator abuse' at ceremonial or retreat settings, mostly involving ayahuasca. The authors note sampling bias and self-reported data, and found that callers' satisfaction depended most on whether volunteers seemed genuine and caring.

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